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Description
Synaptosomes A preparation of the presynaptic terminal, often containing a portion of the target cell sometimes amounting to a complete dendritic spine adhering to their external surface

37 To overcome the limitation, surfactants, complexing agents, or nanoparticle formulation might be required

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While AOD-9604 works systemically once absorbed, injecting near the target fat depot provides the highest local concentration during the brief peak activity window
Tesofensine stands out because it targets brain signals linked to hunger

Preprint at bioRxiv (2022)
