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Description
This cysteine-homocysteinylation event perturbs the pro-insulin receptor and furin protease interaction within the Golgi apparatus, consequently inhibiting the cleavage of the pro-insulin receptor
Schaumburg et al., Sensory Neuropathy from Pyridoxine Abuse, N
Occasionally, more significant bruising can occur
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The dose ranges studied spanned from 0.25 mg to 54 mg, allowing for assessment of dose-response relationships in adverse effect profiles
It is done under general anesthesia
