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Meanwhile, less Cu 2+ is reduced to Cu + and then pumped into cells by CTR1, which removes the inhibition effect of Cu + on -secretase activity and promotes the generation of A

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Oncotarget 2017;8:1307384

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J Clin Invest (2014) 124(2):52842

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This last point is speculative

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Effect on oxidative metabolism, exocytosis, cytosolic Ca2+ concentration and inositol phosphate formation

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Such interactions might alter the receptor's configuration, potentially initiating a cascade of molecular events

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