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Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammaging

NHL, non-Hodgkin lymphoma

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Phytomedicine 23(2):114122 Zhao ZQ et al (2016b) Gefitinib induces lung cancer cell autophagy and apoptosis via blockade of the PI3K/AKT/mTOR pathway

Its gradual decline leads to impaired mitochondrial function, reduced DNA repair, and dysregulation of gene expressionall factors that accelerate cellular decline

However, there is evidence suggesting that they could contribute to alter the molecular mechanisms involved in the pathogenesis of PD