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Description
Sherer TB, Betarbet R, Greenamyre JT
JAMA Intern
Mitochondria and synaptic plasticity in the mature and aging nervous system
For example, they can protect mitochondria (e.g., SS-31, which reduces ROS and apoptosis) and boost antimicrobial defense (e.g., LL-37, which prevents bacterial translocation in sepsis)
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They noted that cellular activity, energy and respiration were depressed by approximately 40% in older individuals
