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This observation is supported by clinical studies showing that chronic stress and dysregulation of the stress response were found to contribute to the maintenance and propagation of various CSCs in patients suffering from chronic stress, anxiety, depression, and suicidal behaviour [226, 251, 252]

doi: 10.1002/cbf.3163 161

Furthermore, research has shown it activates interferon-gamma production in T-cells, which is crucial for immune defense

The F/B ratio exhibited a marked decline from 1.2 to below 1.0 subsequent to 7.4 Gy radiation exposure

The GPx1 allelic loss of pathologically normal tissue adjacent to tumors would be an early event in cancer progression

[DOI] [PMC free article] [PubMed] [Google Scholar] 174.Yuan M.Q., Song L., Wang Z.R., Zhang Z.Y., Shi M., He J., Mo Q., Zheng N., Yao W.Q., Zhang Y., et al