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doi: 10.1186/1742-2094-7-46

The complex role of TIGAR in nervous system diseases and its neuroprotective effects through different mechanisms need to be further revealed, including potential agonists, inhibitors and related pathways, so as to provide references for the research of TIGAR-targeted drugs
[DOI] [PMC free article] [PubMed] [Google Scholar] 235.Fusar-Poli L., Rutten B.P.F., van Os J., Aguglia E., Guloksuz S
When mitochondrial DNA volume and integrity are compromised, free radicals proliferate, and cell damage occurs, leading to accelerated aging and wrinkles
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