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For example, creatine can act as an exocytosis transmitter by nerve cells [51] and adjust gamma-aminobutyric acid (GABA) receptors (inhibitory [52] or stimulant [53])

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Whereas the first randomized, double-blind, cross-over study with bilateral cathodal cerebellar stimulation showed no effect on essential tremor [155], the second study in which anodal tDCS was applied over the dorsolateral prefrontal cortex showed an improvement in ADL (i.e., Activities of Daily Living) scores and TETRAS (i.e., The Essential Tremor Rating Assessment Scale) scores [211]

Adverse Pregnancy Outcomes During pregnancy, high Hcy can cause complications like high blood pressure (e.g., preeclampsia), repeated miscarriages, birth defects, and premature birth