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Targeting Multidrug Resistance Protein 1 (MRP1, ABCC1): Past, Present, and Future. Annual Review of Pharmacology and Toxicology 54: 95117

Bot Rev 87(4):421466

The N-terminal domain (amino acid residues 1167) folds into an antiparallel four-helix bundle

Checkpoint Kinase 1 Inhibition Enhances Cisplatin Cytotoxicity and Overcomes Cisplatin Resistance in SCLC by Promoting Mitotic Cell Death

This new paradigm subverts traditional theories underlying the development of autoimmunity, which are based on molecular mimicry and/or the bystander effect, and suggests that the autoimmune process can be arrested if the interplay between genes and environmental triggers is prevented by re-establishing intestinal barrier function

doi: 187
