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Membrane defects: Membrane defects decrease RBC lifespan, e.g
As a result there is a selective enrichment in red blood cells that, despite being genetically G6PD deficient, have relatively higher levels of G6PD
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References 1.Bieber C., Ramirez A
Rombaldi Bernardi J, de Souza Escobar R, Ferreira CF, Pelufo Silveira P
In intraerythrocytic trophozoite parasites, the drug blocks detoxification of heme, a byproduct of hemoglobin degradation [6]
