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Most side effects are mild and manageable with dosage adjustments

Chronic treatment requirements further complicate therapy, particularly in elderly patients with multiple comorbidities who are highly susceptible to adverse drug reactions and drugdrug interactions (Cummings et al., 2019

For example, use of a water soluble solvent provides a high viscosity depot when the solvent diffuses rapidly out of the injected formulation

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Supporting metabolism, protecting lean mass, and addressing deficiencies early helps prevent the fatigue and plateaus that sometimes occur later in treatment