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Our result indicated that PREOG enhanced semen quality, GSI/EPI, SOD, GPx, and GST values at (PND90), also PREOG upregulates the expression of StAR, 3-HSD, 17-HSD genes, and testosterone value in (PND90), PREOG also upregulated the expression of PTMA, RSPH6A, DAAM1 genes, and the fertility outcome in (PND90) offspring

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Chronic infections like hepatitis, herpes viruses, can suppress and deregulate the immune system