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What is the appropriate vitamin B12 dosing regimen for an alcoholic patient presenting with confusion and a serum B12 level of 156 pg/mL?

In fact, it has proven to be the preferred mode of treatment in numerous countries including Sweden, Norway, and Canada (Nilsson et al., 2005)

In addition, mitochondrial dysfunction in oligodendrocytes results in endoplasmic reticulum stress 8,9,10 , causing further downregulation of myelin proteins 11 and reduced myelin lipid synthesis 4

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Together, they may provide both localized and systemic healing enhancement