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47 Most studies in patients on HD have shown benefits of B12 either on its own or extra benefit when added to other B vitamins (mostly folate)

[DOI] [PubMed] [Google Scholar] 21.Lameire N

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The phosphorylated form of NAD + , NADP/NADPH, parallels NAD + /NADH by functioning as a redox coenzyme in the pentose phosphate pathway, generation of acetyl coenzyme A (acetyl-CoA) for lipid and cholesterol biosynthesis, and in the glutathione and thioredoxin antioxidant systems 4,5,8,9