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doi: 10.1038/309163a0

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No participants developed antibodies against AOD-9604, and no treatment-related serious adverse events led to study withdrawal

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Blockade of CD38 diminishes lipopolysaccharide-induced macrophage classical activation and acute kidney injury involving NF-kB signaling suppression

The splenic M38 316323 specific CD8 + T cells, which reflect the inflationary pp65-specific CD8 + T cells in humans (39), were unchanged in frequencies, but these cells displayed increased KLRG1 and CD44 expression, which is in agreement with the higher viral load following immunosuppression (Figure 8C and Supplemental Figure 8A)