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Much controversy has arisen around overexpression in nematodes and Drosophila, but few attempts have been made to further characterize the tissue-specific roles and define activities of sirtuins in these genetic systems by manipulationfor example, 20 years after the initial studies, no tissue-specific role for nematodes SIR-2.1 has been reported to date

A recent meta-analysis included 5 randomized controlled trials, combining data of 400 participants, examining effects of Ashwagandha on sleep quantity and quality

The case of AIMP2 and alpha-synuclein

N-acetylcysteine (NAC) ameliorates Epstein-Barr virus latent membrane protein 1 induced chronic inflammation

At the end of the study, 33% of the Pycnogenol subjects reported the complete disappearance of leg heaviness and 63% did not feel any swelling

A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma