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Thirty years of saying NO: sources, fate, actions, and misfortunes of the endothelium-derived vasodilator mediator

We discuss how ME/CFS emerges from an intricate web of genetic vulnerabilities and environmental triggers, notably viral infections, leading to a complex series of pathological responses including immune dysregulation, chronic inflammation, gut dysbiosis, and metabolic disturbances

Serious adverse reactions from degradation products in properly sealed medication are rare

In addition to enzymatic degradation, chemical methods have been used both to modify the structure of mucus for drug delivery and to treat mucus overproduction

While molecular mechanisms and output of the central clocks are relatively well studied, how the clocks in different peripheral tissues receive and process time-of-the-day information to exert tissue-specific functions in Drosophila is still poorly understood

Piccirillo JF, Finnell J, Vlahiotis A, Chole RA, Spitznagel E