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Description
ROS and oxidatively modified macromolecules function as damage-associated molecular patterns (DAMPs), engaging pattern recognition receptors (PRRs) on microglia, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), to initiate inflammatory cascades ( Microglia, the resident immune cells of the CNS, are tightly regulated under physiological conditions to maintain neural homeostasis

This patient's lack of primary gastrointestinal malignancies and presence of a parafollicular cell neoplasm make a DNA mismatch repair gene mutation unlikely

Lipid nanoparticles-rom liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement
NMR-based observations of oxidation kinetics on the time scale of seconds To explore the potential of LLC for the detection of fast oxidation processes, we monitored the transformation of glutathione, GSH, into its oxidized form, glutathione disulfide, GSSG (Fig
10.1016/B978-0-12-397153-1.00005-6 25 BalakrishnanR.VijayrajaD.JoS

Transpl Immunol (2015) 32(1):4650
