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But now that my arm itches so much, Im wondering if its a vaccine reaction, too

Sigma-1 receptor (Sigmar1), a specific chaperone located in mitochondria-associated endoplasmic reticulum membranes (MAMs), interacts with the SERCAs to catalyse the production of mitochondrial ATP, which carries Ca 2+ reabsorption from the cytoplasm and carries calcium ions from the cytoplasm to the endoplasmic reticulum, a process that generates Ca oscillations and thus affects bone homeostasis in RA

That does not mean the treatment creates dramatic change for everyone or works the same way for everybody

in m , *p = 0.0208, **p = 0.0080

Bone disorder and bone growth

Liu X, Ge Y, Yu Q, Liu Y, Zhang W, Yin T (2024) Seasonal variability of global intraseasonal SST perturbations from 1982 to 2021