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Peptide-bond modified glutathione conjugate analogs modulate GSTpi function in GSH-conjugation, drug sensitivity and JNK signaling

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Mol Genet Metab (2010) 99:5861.10.1016/j.ymgme.2009.08.005 102 FryeRERossignolDA

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Critical role of oxidative stress in tumorigenesis Oxidative stress promotes tumorigenesis The relationship between oxidative stress and tumors includes: oxidative stress can cause DNA oxidative damage, leading to gene mutations and cancer initiation

SeNPs increase their ability to penetrate the BBB when bound to specific compounds