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Because cancer cells do not take up aspartate very well, GOT fuels tumorigenesis by providing cytosolic aspartate, which is used as a precursor for protein and nucleotide synthesis and for redox homeostasis 32

Zhao L, Varghese Z, Moorhead JF, Chen Y, Ruan XZ

doi: 10.1016/0014-4827(65)90387-3 188 YamamotoY

24(1):92-9 [PubMed Citation]

2013;19(6):704-712.[DOI] 118

Given its energetic requirements, it should be no surprise that researchers are increasingly making connections between the brain and mitochondrial health (mitochondria are power horse organelles found in most cells and are responsible for cellular respiration and energy production)