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Multivitamin and micronutrient treatment improves semen parameters of azoospermic patients with maturation arrest
Cross-trial comparisons are further complicated by the absence of standardized doses (eg, lycopene sources varying from whole tomatoes to supplements) and placebo controls
Broader solid tumor studies corroborate that pharmacological inhibition of CAF-mediated Gln synthesis disrupts tumor metabolic fitness, suggesting combinatorial targeting of tumoral and stromal glutamine metabolism, particularly through dual GLS1/ECM pathway inhibition, may offer promising therapeutic avenues for advanced prostate cancer (196)
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