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In addition, for therapeutic application, it is preferable that an enzyme should have both structural and functional stabilities under severe conditions

So, apart from the effects that are dependent on the dosage, there are also cellular metabolic alterations that depend on time during the course of a toxic event

Other PTMs of NRF2 In addition to the above-mentioned PTMs, NRF2 undergoes a variety of other PTMs that also play important roles in regulating its stability, activity, and cellular localization

Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: relevance to Parkinsons disease