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As mentioned above, the regulation of A by UA may occur secondary to autophagy or microglial activation [217]

Yuen MF, Heo J, Jang JW, Yoon JH, Kweon YO, Park SJ, Tami Y, You S, Yates P, Tao Y, Cremer J, Campbell F, Elston R, Theodore D, Paff M, Bennett CF, Kwoh TJ
& Bagger, J

Notably, Cag pathogenicity island (PAI)-encoded virulence factor CagA manipulates signaling pathways such as ERK/MAPK, NF-KB, leading to pathologic alterations in cell morphology, adhesion, polarity, proliferation, and motility (Wang et al., 2023)

Prevalence rates in multiple sclerosis increase with the patients latitude, and scientific studies have proven that colder climates are harsher for our immune and central nervous systems

Cancer 21 (1), 132
