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Finally, we show that intratumoural delivery of our senolytic and a Braf inhibitor can successfully eliminate early melanomas in a mouse model resulting in increased survival and systemic delivery of our senolytic can eliminate senescent cells in old mice

Mastromatteo M, Chillo S, Civica V, Iannetti M, Suriano N, Del Nobile MA

Kopka, Aina Nicols, Safura Abdool Karim, Meena B
2014;3:e02523.[DOI] 74

The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy
