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This potential benefit was also confirmed by two pilot, randomized, controlled, and open-label clinical trials in early-stage SARS-CoV-2 infected people, in which quercetin phospholipids supplementation has been shown, in combination with standard care, to shorten the timing of molecular test conversion from positive to negative and, at the same time, to reduce the symptom severity and negative predictors of SARS-CoV-2 [94,95]

The plant features dark reddish-brown fibrous roots, upright stems ranging from 1060 cm with a brown-red surface, leaves arranged in two rows, oval-shaped capsules that are oblate-spherical and sessile, female flowers are located at the proximal end, while male flowers are found at the distal end (Rossignol et al., 1987)

Current therapeutic approaches, such as disease-modifying anti-rheumatic drugs (DMARDs) and biologics, are limited by infection risks, poor tissue specificity, and suboptimal long-term efficacy, underscoring the need for novel therapies

For this reason, the presence of MDA levels indicates more tissue damage due to the impairment of the antioxidants activities to deal with oxidative stress and with the handling of free radicals [43]