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With age, mitochondria undergo a progressive deterioration, manifesting as changes in mitochondrial morphology, abundance, and OXPHOS activity 3,4

In contrast, GO is a nanoscale 2D carbon sheet traditionally synthesized through chemical oxidation of pure crystalline graphite using the modified Hummers method

In mouse models of ASCVD (e.g., LDLR -/- ), a high-fat diet expands bone marrow progenitors and promotes myelopoiesis, accompanied by long-term epigenetic changes linked to NLRP3 inflammasome activation and increased IL-1 secretion

A possible explanation of these findings is the fact that increasing temperature augments hydrophobic interaction at the NAC region of -synuclein

Cell Stem Cell 31 , 11011112 (2024)