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In the UN condition, gene ontology (GO) enrichment included Mitochondrial RNA 3-End Processing (GO:0000965), Ribosome Disassembly (GO:0032790), and Mitochondrial Translation (GO:0032543)

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Zhang P, Fu YY, Zhao HM, Liu XY, Wu XH, Lin TF, Wang HQ, Song L, Fang YP, Lu WJ, Liu MJ, Liu WB, Zheng DW

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Because many of these redox systems are diverged from GSH or Trx, yet are found in pathogens and essential to virulence, they are of interest as possible drug targets

This effect was reversed by co-expression of the wild-type PGRMC1 but not of the Y113F mutant, suggesting that PGRMC1 enhances doxorubicin resistance of cancer cells by facilitating its degradation via cytochromes P450