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Cell culture plates were then incubated at 39C for 60 min without CO 2 before measuring oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) in the Seahorse analyzer

Large interindividual variability exists in vitamin A conversion efficiency, and the coefficient of variation has been reported to be as high as 221% [17]

In clinical trials, tirzepatide produced dose-dependent weight loss, with higher doses (10 mg and 15 mg weekly) achieving greater reductions than lower doses
