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The colour change typically resolves within a few days to weeks but has been reported up to 35 days post administration
Bottom line: Employment drug testing won't detect peptides

[DOI] [Google Scholar] Romero A

Paeoniflorin exerts neuroprotective effects in a transgenic mouse model of Alzheimers disease via activation of adenosine A(1) receptor

An alternative approach escalates both agents simultaneously but at slower intervals, extending the total escalation period to twenty weeks or longer