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doi: 10.1093/ajcn/63.3.306 Pubmed Abstract CrossRef Google Scholar View reference in article 65 CoppenA

MOTS-c improved insulin sensitivity and reduced obesity in diet-induced obese mice by activating AMPK [2]

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This complete absence of tolerability-driven discontinuations represents a remarkable safety finding and indicates that even when mild side effects occurred, they were sufficiently manageable that participants chose to continue treatment

Only use it in 15-20 minute increments, which will prevent any long-term damage