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Primary Handling Editor: Sonia Muliyil, in collaboration with the Nature Medicine team

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IM injections into the same muscle group create cumulative microtrauma that alters local blood flow and lymphatic drainage, which degrades absorption consistency by week 46 of a protocol

Across six randomised, double-blind, placebo-controlled trials involving over 900 participants, the adverse event profile was essentially identical to placebo

Cattle, Horses, Swine and Sheep - 1 to 2 ml Dogs and Cats - 0.25 to 0.5 ml May be repeated once or twice weekly, as indicated by condition and response
