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Excessive alcohol consumption increases susceptibility to immune-related conditions, such as: Alcohol and the COVID-19 vaccine A 2023 review aimed to explore alcohols effects on the COVID-19 vaccine by looking at the available research

Yamaguchi M, Weitzmann MN

Importantly, due to its ecto-enzymatic activity, CD38 not only regulates intracellular and extracellular NAD homeostasis, but also modulates the availability of extracellular NAD and its metabolites [6, 57]

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