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INH is a prodrug that enters the Mtb cytoplasm via passive diffusion, where it inhibits mycolic acid synthesis by targeting the InhA enzyme, an essential catalyst in an early step of the mycolic acid biosynthetic pathway (Mitchison, 1956)
The monographs broaden the record, but they do not create symmetry of evidence across all seven candidates
It should be noted, however, that further studies are required to determine if these associated polymorphisms account for the ethnic differences in acetaminophen pharmacokinetics
At Avita MD, we use IV therapy to support your health alongside the daily habits that matter most, and your provider reviews your overall health before recommending a formulation
