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Nat Chem Biol 11:915 Whitaker H, Patel D, Howat WJ et al (2013) Peroxiredoxin-3 is overexpressed in prostate cancer and promotes cancer cell survival by protecting cells from oxidative stress

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An attenuated form of the latter may be seen following intravesical therapy with Bacillus CalmetteGuerin (BCG) for bladder cancer

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The hydrolytic cleavage of its 6-nitro-2,3-dihydroimidazo [2,1-b] oxazole moiety generates M1, which undergoes further transformations involving hydroxylation and oxidation, mediated largely by CYP3A4 (Szumowski and Lynch, 2015

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Metabolomics has recently offered great scientific support for identifying new therapeutic targets and enhancing conventional treatment approaches

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