labial melanotic macule lip Oral Macule: Symptoms and Treatment Labial Macules: Dark Spots on
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Thomsen G'14 Jacquelyn A

If excessive amounts of free fatty acids accumulate in the body, this can lead to mitochondrial damage, resulting in cells and the animals body suffering from a lack of energy

[DOI] [PMC free article] [PubMed] [Google Scholar] Y., W., J., Y., V., G., N., L., 1999

Myint M, Oppedisano F, De Giorgi V, Kim BM, Marincola FM, Alter HJ, Nesci S (2023) Inflammatory signaling in NASH driven by hepatocyte mitochondrial dysfunctions

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An enzyme known as phosphodiesterase breaks it down so that the cellular response is kept short
