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The compound works primarily by activating an enzyme called AMP-activated protein kinase (AMPK), which influences glucose metabolism, lipid regulation, and cellular energy balance

[DOI] [PubMed] [Google Scholar] [104].Gross CJ, Henderson LM, Savaiano DA

Seventy-nine percent were male, 63% were White, 18% were Black, and 14% were Asian

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( f ) Acetyl-CoA abundance was assessed in cells transduced with shRNA targeting TMLHE with or without supplementation with the indicated doses of acetate (n = 8 technical replicates representative from 2 independent experiments)

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