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Further details on trial design development in ALS are referenced [53, 86,87,88,89]

Both the ciliary body and retina have direct access to blood vessels and are also known to be more sensitive to oxidative stress, increasing the risk in these areas for a variety of oxidative stress-induced eye diseases

showed that ferroptosis leads to a diminished hepatic expression of GPx4: experiments performed on MCD-fed mice revealed a reduced GPx4 expression after RSL-3 (a ferroptosis inducer) administration

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The databases were last accessed on 28 February 2023

[DOI] [PubMed] [Google Scholar] 124.Pandey R.P., Mukherjee R., Chang C.-M