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10 In 1976, Rinderknecht and Humbel 11 isolated two active substances from human serum, which owing to their structural resemblance to proinsulin were renamed insulin-like growth factor 1 and 2 (IGF-1 and 2)

Reactive oxygen species (ROS) are generated through interaction of the excited state chromophore with a variety of substrates, which go on to oxidatively damage biomolecules (37)

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To assess whether the integrin 6 subunit was also crucial in mediating growth of colon organoids in BME, we added the inhibitory integrin 6-specific GoH3 antibody 24 while regularly splitting colon organoid cultures

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