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Schoultz, I

Here are some reasons behind the initial discomfort when embarking on B12 therapy: Detoxification The enhanced B12 levels empower your body to expel built-up toxins with more efficiency
MedlinePlus gives the same general site-quality warning for subcutaneous injections: the site should be healthy and free of visible damage

A case in point is the Jarisch-Herxheimer reaction in patients undergoing treatment for Lyme disease
The concentration of both catecholamines and serotonin were determined by external standard method using peak areas

Our ER nurse inserts a small IV catheter, feeling like a quick pinch similar to blood draws
