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PRPs Role in Cartilage Preservation and Disease Modification Unlike traditional treatments that primarily suppress symptoms , PRP has shown potential to slow OA progression and enhance cartilage repair : A study using MRI imaging found that patients receiving PRP had higher cartilage thickness and lower cartilage degeneration scores compared to those receiving HA (PMID: 35188121)

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Synthesized for research into its role as a Luteinizing Hormone (LH) mimetic, this compound is studied for its interaction with the HPTA axis and its influence on endogenous steroidogenesis in experimental models

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In nonresponsive cases, doctors can consider using parenteral B12, especially if oral B12 treatment has been used in the past or when serum vitamin B12 is not normalized (Table 2)

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Schedule: Daily subcutaneous injections for 812 weeks (extend to 16 weeks if desired), followed by a 24 week pause to resensitize receptors

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