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When your B12 levels are low, these processes slow down and you may feel tired and sluggish

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The disconnect between preclinical efficacy and human clinical outcomes remains unexplained and represents a significant limitation for potential therapeutic applications

This systematic approach ensures research quality, enables meaningful comparison with published literature, and contributes to the evidence base that may eventually support regulatory evaluation of BPC-157 for potential therapeutic applications

Author Contributions All authors contributed to the conception and design of the review

Patients with this condition or those with a family history suggestive of Lebers disease should avoid cyanocobalamin-containing products or use alternative forms of vitamin B12 such as hydroxocobalamin under careful medical supervision