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Gabrielli M, Bonazzi P, Scarpellini E, Bendia E, Lauritano EC, Fasano A, et al

Contraindications include pregnancy, active cancer, uncontrolled endocrine disorders, severe cardiovascular disease, and known peptide hypersensitivity

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It is possible, perhaps likely, that studies return lower effect sizes if they are conducted among people from Western, Educated, Industrialised, Rich and Democratic countries (WEIRD, Henrich et al., Reference Henrich, Heine and Norenzayan2010), not least because WEIRD people are also ODD that is, they are relatively old, and live in deodorised and desensitised conditions (Roberts et al., Reference Roberts, Havlek and Schaal2020a)