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Treatment of astrocytes with GGC significantly reduced caspase 3 activity (Figure 1B), supporting the protective effects of GGC against oligomeric A 40 -mediated apoptosis
A key mechanism underlying melatonins antioxidant potential is its direct interaction with free radicals

These microbial metabolites could participate in CNS anti-inflammatory signaling and chromatin remodeling, ultimately enhancing brain homeostasis

3.1.1.4 Disease validation and therapeutic translation The mechanistic insights above converge on a common pathological axis: RSS deficiency chronic NF-B hyperactivation tissue damage

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