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however, prolonged exposure or higher doses may induce oxidative stress, DNA fragmentation, and apoptotic signaling in cardiomyocytes or endothelial cells [131, 132, 135]

PMID: 120 LevinERHammesSR

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Uncoupling of the glial and neuronal mechanisms of synaptic homeostasis, such as physiological pruning and neurotransmitter recycling, may be a central link to synaptopathy

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