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Hypervitaminosis D and acute interstitial nephritis: tale of injections

elegans homologs of GPX4 decreases lifespan (Sakamoto et al., 2014), but whether ferroptosis mediates this is unknown

doi: 10.1016/j.celrep.2013.01.009

Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126/science.abe9985

Abstract Ferroptosis is a newly identified form of cell death that differs from autophagy, apoptosis and necrosis, and its molecular characteristics include iron-dependent lipid reactive oxygen species accumulation, mitochondrial morphology changes, and membrane permeability damage

Key epigenetic factors such as NEUROD2 and MECP2 play significant roles in epilepsy