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Although many studies have failed to measure NRF2 expression after sleep deprivation, most available data from systematically reviewed animal studies suggest an increased expression of key antioxidant enzymes regulated by NRF2, such as GSH, GPx, CAT, and SOD (Villafuerte et al

Given that the dogs were free to run at their own pace for the prescribed distance, the activity points quantify the intensity of the exercise ( 16 )

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