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They are referred to as vitamers having vitamin activity as a coenzyme, meaning that its presence is required for some enzyme-catalyzed reactions

Malabsorption (insufficient absorption of vitamin B12 in the intestine) due to insufficient production of intrinsic factor (a protein produced in the lining of the stomach that is needed to absorb vitamin B12), disorders in the end section of the ileum (part of the small intestine), such as sprue, fish tapeworm infestation or blind loop syndrome (change in the course of the intestine after gastric surgery)
You may feel a slight sting as the needle is inserted

5-HTP is converted into serotonin by the enzyme hydroxytryptophan decarboxylase and with the help of vitamin B6

This effect is usually short-lived and goes away by itself
