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Using these validated tools, we analyzed serum samples from rats and monkeys injected subcutaneously with GX-G3 (1, 3 or 10 mg/kg once a week for 4 weeks followed by a 4-week recovery period) to determine immunogenicity response and toxicokinetic parameters with serum concentration of GX-G3

This is important because rapid IV administration can lead to sudden shifts in electrolytes particularly potassium which may result in hypokalemia and, in severe cases, cardiac complications

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