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As described above, perilipins can be associated with LD biogenesis, but can also have many other functions involved in stabilization and mobilization of the LD (Sztalryd and Brasaemle 2017)
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Clonal excess (CE) light chain expression in blastic phase chronic myeloid leukemia (B1 CML), acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL)
Over weeks and months, this compounds into significant fat loss - especially when combined with proper nutrition and training
At the molecular level, acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3) are key enzymes regulating PUFA incorporation into phospholipids

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